Online consultation, lab work at home, and sermorelin shipped to your door. A US licensed clinician reviews your case and writes the prescription only if it makes sense for you.
Start your Negley consultation
Negley sits in Columbiana County in eastern Ohio, near the Pennsylvania line along Beaver Creek. Specialist medicine concentrates in Youngstown and Pittsburgh — both more than half an hour away. Telehealth keeps that drive optional.
Growth hormone output peaks in the early twenties and declines roughly 1 to 2 percent per year thereafter. By the late forties, daily GH secretion typically sits at half its peak. The pituitary somatotrophs remain intact — what fades is hypothalamic GHRH pulse amplitude, especially the overnight bursts that drive slow-wave sleep IGF-1 production.
Sermorelin is the bioactive 29-amino-acid N-terminal fragment of native GHRH. Injected subcutaneously in the evening, it binds the GHRH receptor on the anterior pituitary and triggers a pulse of endogenous growth hormone. That pulse drives hepatic IGF-1 synthesis through deep sleep. Feedback regulation through somatostatin remains intact; supraphysiologic exposure does not occur.
Recombinant somatropin substitutes for the pituitary entirely. Plasma GH rises sharply and stays elevated, suppressing endogenous output. Sermorelin amplifies the existing rhythm rather than replacing it. If pituitary reserves are exhausted, sermorelin will not work; otherwise, it produces measurable IGF-1 lift with a substantially lower exposure footprint.
The initial intake video runs 40 to 50 minutes. Lab orders route to the Quest Diagnostics in East Liverpool or a Labcorp draw site in Salem.
0.2 to 0.3 mg subcutaneously nightly, an hour before sleep, on a five-on, two-off schedule. Cycles run three to six months with IGF-1 retest at week ten.
Prescriptions dispense from a 503A compounding pharmacy under USP General Chapter <797>. Each lot ships with a certificate of analysis listing identity, purity by HPLC, and sterility by membrane filtration.
| Item | Range |
|---|---|
| Consult | $99 – $200 |
| Labs | $100 – $250 |
| Monthly Rx | $250 – $450 |
Adults 30 to 65 qualify. Cancer and pregnancy are exclusions. Insurance does not cover sermorelin for adult wellness use.
The therapy works as a multiplier. Negley patients who walk Beaver Creek State Park at dawn, sleep cool and dark, and lift two to four times a week consistently report stronger responses. Skipping a high-glycemic snack within an hour of the evening injection preserves the GH pulse — elevated insulin blunts the pituitary response sharply. After the first cycle, most settle into a quarterly video check-in with one fasting lab visit between calls.
No clinic visit. No insurance forms. A clinician licensed in Ohio reviews your intake and labs, decides whether sermorelin fits, and writes a prescription to a partner compounding pharmacy that shipped to your address in Negley.
01
Twenty-minute health questionnaire on energy, sleep, recovery and history. Asynchronous, on your phone, no waiting room.
02
A blood draw kit is sent to your home or a partner lab is scheduled near you. IGF-1, fasting glucose, full metabolic panel.
03
A licensed clinician in your state reads your file and decides whether sermorelin is medically appropriate. If not, full refund.
04
Compounded sermorelin arrives with insulin syringes, alcohol pads and a clear dosing protocol. A 1:1 health coach is included.
Pricing is bundled. The intake, the clinician review, the labs and the medication ship together as a single program. Most plans run between 180 and 240 dollars per month depending on dose and format. HSA and FSA cards are accepted at most partner providers.
Final pricing varies by clinician and pharmacy and is presented before any commitment.
Sermorelin works on a slow curve because it asks the body to make its own growth hormone. Results compound over months, not days. A typical reported timeline looks like this.
Weeks 1 to 4
Deeper sleep is usually the first signal. Morning energy lifts. Recovery from training feels faster. No measurable body composition change yet.
Weeks 5 to 8
Skin texture, hair quality and nail strength tend to shift. Mental clarity in the afternoon improves. Strength on lifts often goes up.
Weeks 9 to 12
Body composition starts moving, with a typical 5 to 10 percent fat reduction reported alongside small lean mass gains. Libido and joint comfort improve.
Month 4 and beyond
A follow-up IGF-1 lab is drawn. Dose is adjusted up or down. Many patients maintain on a lower dose after this point.
Yes. A clinician licensed in your state writes a prescription to a partner compounding pharmacy. The medication is dispensed under federal sections 503A and 503B by a registered pharmacy. You receive a copy of the prescription with your shipment.
No. The whole flow is asynchronous. You complete the intake on your phone, draw the lab at home or at a partner lab, and the clinician reviews your case online. If a video visit is required by your state, it is scheduled at no additional cost.
Sermorelin is legal in Ohio (OH) when prescribed by a clinician licensed in the state. Each state medical board sets its own scope of practice, but compounded sermorelin dispensed under federal 503A and 503B is permitted across all 50 states.
Most national telehealth networks operate in all 50 states and can transfer your case to a clinician licensed in the new state. Your prescription continues without a break.
Yes. Subscriptions are cancelable from your dashboard. You keep what has already shipped and you are not charged again. There is no minimum commitment beyond the standard 12 week protocol that is recommended for clinical reasons.
Reported side effects are generally mild and include injection site redness, transient flushing and occasional headache. Sermorelin uses your own pituitary gland, which tends to be safer than synthetic HGH because the body retains its natural feedback loop.
Compounded peptides are typically not covered by insurance. HSA and FSA cards are accepted by most providers and let you pay with pre-tax dollars. The all-in cost is presented before you commit.
Online intake. Labs at home. A clinician licensed in Ohio decides. If sermorelin is not for you, you get a full refund.
Start your Negley consultation